Does Prolactin Affect Mood?

How does prolactin affect the body?

Prolactin is a hormone produced by your pituitary gland which sits at the bottom of the brain.

Prolactin causes breasts to grow and develop and causes milk to be made after a baby is born.

Normally, both men and women have small amounts of prolactin in their blood..

How does high prolactin make you feel?

Symptoms from the high prolactin levels include discharge of milk from the breast (galactorrhoea) and breast tenderness. These symptoms are more common in women than men. High prolactin levels can also affect the function of the ovaries or testes by interfering with the hormones that control these glands.

Does prolactin make you tired?

Rarely, the prolactinoma may press on the rest of the pituitary gland, stopping it from producing other hormones. This can cause symptoms such as tiredness, fainting, low blood pressure, low blood sugar or collapse.

Can lack of sleep cause high prolactin?

Excess breast manipulation, high protein meals, physical activity and sleep deprivation can artificially elevate the prolactin levels.

Does prolactin cause weight gain?

High levels of prolactin can also result in weight gain and neuropsychological disturbances. The size of the tumor correlates with the amount of prolactin secreted. Larger tumors can cause mass effects by compression of local structures.

What happens if prolactin is high in female?

Excess prolactin can cause the production of breast milk in men and in women who are not pregnant or breastfeeding. In women, too much prolactin can also cause menstrual problems and infertility (the inability to get pregnant). In men, it can lead to lower sex drive and erectile dysfunction (ED).

What happens if prolactin goes untreated?

Left untreated, a prolactinoma may grow large enough to compress your optic nerve. This can cause a loss of peripheral vision. Low levels of other pituitary hormones.

How much prolactin is normal?

Normal Results The normal values for prolactin are: Men: less than 20 ng/mL (425 µg/L) Nonpregnant women: less than 25 ng/mL (25 µg/L) Pregnant women: 80 to 400 ng/mL (80 to 400 µg/L)

What are the side effects of high prolactin levels?

High Prolactin Level SymptomsInfertility.White milk leaking from nipples.Absent, infrequent, or irregular periods.Loss of libido.Painful or uncomfortable intercourse.Vaginal dryness.Acne.Excessive body and facial hair growth (hirsutism)More items…

Does prolactin increase during stress?

Some studies suggest that prolactin secretion during stress acts to maintain homeostasis within the immune system. While glucocorticoids, also released in response to stress, are suppressive immunomodulators, prolactin and growth hormone stimulate the immune system [12].

Does high prolactin affect mood?

Patients with prolactinomas also have reported a higher frequency of depressive symptoms, anxiety, and feelings of hostility than a group of people with either amenorrhea associated with normal prolactin levels or healthy comparison subjects with normal prolactin levels.

Can High prolactin levels cause depression?

Prolactinomas, the most common type of pituitary tumor, can induce hyperprolactinemia and cause some psychiatric symptoms, such as anxiety, depression and even psychotic symptoms.

How long does prolactin last?

Prolactin levels usually fall within the first two to three weeks of treatment, but detectable decreases in adenoma size take more time, usually several weeks to months.

How can I bring my prolactin levels down?

Treatment for high prolactin levelschanging your diet and keeping your stress levels down.stopping high-intensity workouts or activities that overwhelm you.avoiding clothing that makes your chest uncomfortable.avoiding activities and clothing that overstimulate your nipples.taking vitamin B-6 and vitamin E supplements.

Does high prolactin cause hair loss?

According to these results, moderate elevated prolactin levels in association with diffuse or androgenetic hair loss can be neglected as causative for the hair loss, because there is no evidence that they have an influence to the pattern, the extent or the duration of the hair loss.

What can I eat to reduce prolactin?

Foods that lower prolactin levels are generally high in zinc; think shellfish, beef, turkey and beans. It’s also important to get plenty of B6, so foods like potatoes, bananas, wild salmon, chicken and spinach can help boost those vitamin levels.

Can stress cause prolactin levels to rise?

Certain medications and low thyroid may raise prolactin levels. Commonly, small pituitary tumors will cause hyperprolactinemia as well, with no other abnormalities. Prolactin is a stress hormone and modest elevations of prolactin are seen with exercise, eating, stress, and/or nipple stimulation.

What is prolactin responsible for?

Prolactin contributes to hundreds of physiologic functions, but the two primary responsibilities are milk production and development of mammary glands within breast tissues. Prolactin promotes the growth of mammary alveoli, which are the components of the mammary gland, where the actual production of milk occurs.

Does prolactin affect sleep?

Similar to growth hormone secretion, prolactin secretion is more strongly related to sleep onset, although some circadian input occurs. Prolactin levels are associated with slow-wave sleep, and interrupted sleep results in blunting of the nighttime rise.

Is prolactin a stress hormone?

Prolactin (PRL) is one of the most versatile hormones known. It is considered an adaptive hormone due to the key roles it plays in the modulation of the stress response and during pregnancy and lactation.

Does high prolactin always mean tumor?

One common cause of hyperprolactinemia is a growth or tumor on the pituitary gland called a prolactinoma. The tumor produces high levels of prolactin. These tumors can be large or small and are usually benign, meaning they are not cancerous.